Frontiers An overview of agents and treatments for PDGFRA

lt;p>Platelet-derived growth factor receptor A (PDGFRA) mutations occur in approximately 10–15% of gastrointestinal stromal tumors (GISTs). These tumors with P

Targeting the PDGF/PDGFR signaling pathway for cancer therapy: A review - ScienceDirect

Discovery and pharmacological characterization of AZD3229, a potent KIT/PDGFRα inhibitor for treatment of gastrointestinal stromal tumors

Reactome Signaling by PDGFR in disease

Gastrointestinal Stromal Tumors: The GIST of Precision Medicine.

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Mutation Analysis: Kit and PDGFRA

Ripretinib for the treatment of advanced gastrointestinal stromal tumor - John R. Zalcberg, 2021

Full article: PDGF as an Important Initiator for Neurite Outgrowth Associated with Fibrovascular Membranes in Proliferative Diabetic Retinopathy

Patient disposition. Abbreviations: GIST, gastrointestinal stromal

Frontiers Characterization of prevalent tyrosine kinase inhibitors and their challenges in glioblastoma treatment

Frontiers Case Report: Evolution of KIT D816V-Positive Systemic Mastocytosis to Myeloid Neoplasm With PDGFRA Rearrangement Responsive to Imatinib